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Luteoethanones A and B, two phytotoxic 1-substituted ethanones produced by Neofusicoccum luteum, a causal agent of Botryosphaeria dieback on grapevine.

Marco MasiPierluigi RevegliaGiuseppe FeminaRegina Baaijens-BillonesSandra SavocchiaAntonio Evidente
Published in: Natural product research (2020)
Two new phytotoxic 1-substituted ethanones, named luteoethanones A and B, were isolated from Neofusicoccum luteum, the causal agents of Botryosphaeria dieback in Australia. Luteoethanones A and B were characterized, by spectroscopic methods (essentially 1 D and 2 D NMR and HR ESIMS), as 1-(8-Methoxy-2,4-methyl-1-oxa-4-aza-spiro[2.5]octa-5,7-dien-6-yl)-ethanone and its 2-demethyl analogue. When assayed on detached grapevine leaves (Vitis vinifera cv. Shiraz) both the compounds showed phytotoxic activity.
Keyphrases
  • molecular docking
  • magnetic resonance
  • molecular dynamics simulations
  • high resolution
  • acinetobacter baumannii
  • klebsiella pneumoniae
  • solid state
  • escherichia coli
  • drug resistant