Novel quinolone resistance determinant, qepA8, in Shigella flexneri isolated in the United States, 2016.

Hattie E WebbKaitlin A TaggJessica C ChenJustin KimRebecca LindseyLouise K Francois WatkinsBeth E KarpYo SugawaraJason P Folster

Published in: Antimicrobial agents and chemotherapy (2019)

Enterobacteriaceae, quinolone resistance is largely attributed to mutations in the quinolone resistance-determining regions (QRDR) of gyrA, gyrB, parC, and parE, and plasmid-italiciated quinolone resistance (PMQR) genes (e.g., qnr genes, aac(6')-Ib-cr, or qepA).….

Keyphrases

genome wide
escherichia coli
pseudomonas aeruginosa
multidrug resistant
gene expression