Obesogenic Diet Cycling Produces Graded Effects on Cognition and Microbiota Composition in Rats.

Michael D KendigSarah-Jane LeighKyoko HasebeNadeem O KaakoushR Fred WestbrookMargaret J Morris

Published in: Molecular nutrition & food research (2023)

Results suggest that diet-induced cognitive deficits worsen in proportion to unhealthy diet exposure, and that shifting to a healthy chow for at least a week is required for recovery under the conditions tested here.

Keyphrases

weight loss
physical activity
mild cognitive impairment
high intensity
clinical trial
white matter