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Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations.

Ana MarquezMartin KerickAlexandra ZhernakovaJavier Gutierrez-AchuryWei-Min ChenSuna Onengut-GumuscuIsidoro González-ÁlvaroLuis Rodriguez-RodriguezRaquel Rios-FernándezMiguel A González-Gaynull nullnull nullnull nullnull nullMaureen D MayesSoumya RaychaudhuriStephen S RichCisca WijmengaJavier Martín
Published in: Genome medicine (2018)
In this study, we have been able to advance in the knowledge of the genetic overlap existing in autoimmunity, thus shedding light on common molecular mechanisms of disease and suggesting novel drug targets that could be explored for the treatment of the autoimmune diseases studied.
Keyphrases
  • systematic review
  • electronic health record
  • genome wide
  • emergency department
  • meta analyses
  • big data
  • dna methylation
  • case control
  • data analysis
  • smoking cessation