HIV-1 transmitted drug resistance in newly diagnosed individuals in Italy over the period 2015-21.
Lavinia FabeniDaniele ArmeniaIsabella AbbateRoberta GagliardiniValentina MazzottaAda BertoliWilliam GennariFederica ForbiciGiulia BernoLorenzo PiermatteoVanni BorghiCarmela PinnettiAlessandra VergoriAnnalisa MondiGiustino ParrutiFiorella Di SoraMarco IannettaMiriam LichtnerAlessandra LatiniCristina MussiniLoredana SarmatiCarlo Federico PernoEnrico GirardiAndrea AntinoriFrancesca Ceccherini-SilbersteinFabrizio MaggiMaria Mercedes Santoronull nullPublished in: The Journal of antimicrobial chemotherapy (2024)
Between 2015 and 2021, TDR prevalence in Italy was 8% and remained almost stable over time. Resistant strains were found circulating regardless of being in TCs, but less likely in non-B subtypes. These results highlight the importance of a continuous surveillance of newly diagnosed individuals for evidence of TDR to inform clinical practice.