Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid.

Johan GobomLucilla ParnettiPedro Rosa-NetoMartin VyhnalekSerge GauthierSamuela CataldiOndrej LerchJan LaczoKateřina VeverováMarcus ClarinAndrea I BenetTharick A PascoalNeserine RahmouniManu VandijckElse HuyckNathalie Le BastardJenna StevensonMira ChamounDaniel AlcoleaAlberto LleóUlf AndreassonMarcel M VerbeekGiovanni BellomoRoberta RinaldiNicholas AshtonHenrik ZetterbergKaterina SheardovaJakub HortKaj Blennow

Published in: Clinical chemistry and laboratory medicine (2021)

Our results suggest that the LUMIPULSE G assays for the CSF AD biomarkers are fit for purpose in clinical laboratory practice. Further, they corroborate earlier presented reference limits for the biomarkers.

Keyphrases

cerebrospinal fluid
high throughput
primary care
machine learning
single cell
label free