Urinary complement proteins in IgA nephropathy progression from a relative quantitative proteomic analysis.

Xia NiuShuyu ZhangChen ShaoZhengguang GuoJianqiang WuJianling TaoKe ZhengWenling YeGuangyan CaiWei SunMingxi Li

Published in: PeerJ (2023)

There were abundant complement components in the urine of IgAN patients, indicating that the activation of AP and LP is involved in IgAN progression. Urinary complement proteins may be used as biomarkers for evaluating IgAN progression in the future.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
high resolution
transcription factor
patient reported
mass spectrometry