Hematological and genetic profiles of persons with co-inherited heterozygous β-thalassemia and supernumerary α-globin genes.

Durga Devi SundaresanJasbir Kaur HiraSanjeev ChhabraAmita Trehan Alka Rani Khadwal Pankaj Malhotra Prashant Sharma Reena Das

Published in: European journal of haematology (2023)

state for the first time in such genotypically-complex Indian cases. Supernumerary α-genes should be suspected in all βTT with disproportionate clinical symptoms, mild-to-moderately elevated HbF, and unexplained anisopoikilocytosis.

Keyphrases

genome wide
bioinformatics analysis
genome wide identification
dna methylation
early onset
genome wide analysis
copy number
gene expression
physical activity
sleep quality
sickle cell disease
transcription factor