11,12-Diacetyl-carnosol Protects SH-SY5Y Cells from Hydrogen Peroxide Damage through the Nrf2/HO-1 Pathway.

Qingyi Luo Weiyan HuHaofei YuRong-Ping Zhang Xinglong Chen

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

-induced neurotoxicity by activating the Nrf2/HO-1 pathway. Thus, the neuroprotective and antioxidative stress effects of NO.20 may make it a promising neuroprotective compound for AD treatment.

Keyphrases

hydrogen peroxide
oxidative stress
diabetic rats
nitric oxide
cerebral ischemia
signaling pathway
pi k akt
high glucose
anti inflammatory
stress induced
cell proliferation
blood brain barrier
subarachnoid hemorrhage
replacement therapy