Urine biomarker score captures response to induction therapy with lupus nephritis.
Ellen M CodyScott E WenderferKathleen E SullivanAlfred Hyoungju KimWesley FiggHarneet GhummanTingting QiuBin HuangPrasad DevarajanHermine I BrunnerPublished in: Pediatric nephrology (Berlin, Germany) (2023)
The RAIL biomarkers differentiate LN patients based on activity of kidney disease, with decreases of ≥ 1 in pRAIL scores indicating complete response to induction therapy. Significantly lower RAIL scores in healthy controls and in SLE patients without known LN raise the possibility of subclinical kidney disease. A higher resolution version of the Graphical abstract is available as Supplementary information.