The APOE4 allele is associated with a decreased risk of retinopathy in type 2 diabetics.
Lucie DlouhaTerezie PelikanovaJiří VelebaVera AdamkovaVera LanskaTomas SosnaLukas PacalKaterina KankovaJaroslav Alois HubacekPublished in: Molecular biology reports (2021)
Common APOE polymorphism was not associated with T2DM in the Czech population. Yet, APOE4 allele revealed an association with retinopathy. In particular, female T2DM patients with at least one APOE4 allele exhibit lower prevalence of retinopathy in our study subjects.