Intraocular RGD-Engineered Exosomes and Active Targeting of Choroidal Neovascularization (CNV).

Dimitrios PollalisDongin KimGopa Kumar Gopinadhan Nair Chang Sun KangArjun V NandaSun Young Lee

Published in: Cells (2022)

Intravitreally delivered retinal multicell-derived exosomes have good retinal penetration, and ASL modification of exosomes actively targets CNV with no immediate reactive gliosis. ASL exosomes have a great potential to serve as an intraocular drug delivery vehicle, allowing an active targeting strategy.

Keyphrases

mesenchymal stem cells
optical coherence tomography
stem cells
diabetic retinopathy
drug delivery
cancer therapy
optic nerve
cerebral blood flow
cataract surgery
risk assessment
climate change
drug release