Plasmodium falciparum gametocytes display global chromatin remodelling during sexual differentiation.
Myriam D JeningaJingyi TangShamista A SelvarajahAlexander G MaierMichael F DuffyMichaela PetterPublished in: BMC biology (2023)
Collectively, we defined novel combinatorial chromatin states differentially organising the genome in gametocytes and asexual parasites and unravelled fundamental, sex-specific differences in the epigenetic code. Our chromatin maps represent an important resource for future understanding of the mechanisms driving sexual differentiation in P. falciparum.