Effects of hypertonic saline versus mannitol in patients with traumatic brain injury in prehospital, emergency department, and intensive care unit settings: a systematic review and meta-analysis.

Yukari MiyoshiYutaka KondoHidetaka SuzukiTatsuma FukudaHideto YasudaShoji Yokoborinull null

Published in: Journal of intensive care (2020)

Our findings revealed no significant difference in the all-cause mortality rates between patients receiving hypertonic saline or mannitol to control intracranial pressure. Further investigation is warranted because we only included a limited number of studies.

Keyphrases

traumatic brain injury
intensive care unit
emergency department
cardiac arrest
mechanical ventilation
single cell
case control
trauma patients
emergency medical
optic nerve
extracorporeal membrane oxygenation
drug induced