Association of serum CTRP4 levels with vascular endothelial function in patients with type 2 diabetes mellitus: CTRP4 ameliorating inflammation, proliferation and migration in human umbilical vein endothelial cells.

Jie GaoMai Re YanMu RouziHuihui ZhangXinghua CaiBilin XuJun LuTao Lei

Published in: Acta diabetologica (2024)

Serum CTRP4 concentrations were negatively associated with FMD. CTRP4 alleviated proliferation, migration and inflammation in HUVECs through the suppression of NF-κB and STAT3 signaling pathways.

Keyphrases

signaling pathway
oxidative stress
endothelial cells
pi k akt
cell proliferation
induced apoptosis
epithelial mesenchymal transition
lps induced
inflammatory response
nuclear factor
vascular endothelial growth factor