Population pharmacokinetic and optimization of polymyxin B dosing in adult patients with various renal functions.
Xu-Ben YuZheng JiaoChun-Hong ZhangYing DaiZi-Ye ZhouLu HanXin WenChang-Cheng ShengGuan-Yang LinJing-Ye PanPublished in: British journal of clinical pharmacology (2020)
Renal function plays a significant role in polymyxin B PK, and the dose of polymyxin B should be adjusted according to CrCL in patients with renal insufficiency.
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