Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers.

João LoboAd J M GillisAnnette van den BergLeendert H J Looijenga

Published in: BMC cancer (2020)

The informative protein biomarkers (i.e., MIB-1, CXCL12, beta-catenin, and possibly CXCR4) may prove useful for risk-stratifying patients if validated in larger, multicentric and well-defined studies. Currently, classical histopathological features of testicular germ cell tumors remain key for relapse prediction.

Keyphrases

germ cell
end stage renal disease
newly diagnosed

ejection fraction
chronic kidney disease

prognostic factors
public health

cell proliferation
epithelial mesenchymal transition