Copper-catalyzed dicarbonyl stress in NAFLD mice: protective effects of Oleuropein treatment on liver damage.
Silvano Junior SantiniGiovanni TarantinoAntonella IezziAnna AlisiClara BalsanoPublished in: Nutrition & metabolism (2022)
Our study highlights the role of the dicarbonyl stress in the pathogenesis of NAFLD and suggests Ole as a natural copper chelator to prevent the liver damage induced by methyglyoxal pathway derangement.