Discordance between aPTT and anti-Xa in monitoring heparin anticoagulation in mechanical circulatory support.

Song LiAng LiJennifer A BeckmanChristopher KimMarian A GranichJohn MondinDaniel E SabathDavid A GarciaClaudius Mahr

Published in: ESC heart failure (2024)

aPTT and anti-Xa were frequently discordant in MCS patients receiving heparin anticoagulation. Clinical conditions common in MCS patients such as concurrent warfarin use, malnutrition, haemolysis, and thrombocytopenia, as well as durable type of MCS devices were associated with a high aPTT relative to anti-Xa.

Keyphrases

venous thromboembolism
atrial fibrillation
end stage renal disease
direct oral anticoagulants
ejection fraction
newly diagnosed
peritoneal dialysis
squamous cell carcinoma
patient reported outcomes
radiation therapy