The analysis of epidermal nerve fibre spatial distribution improves the diagnostic yield of skin biopsy.

G PiscosquitoVincenzo ProviteraS MozzilloG CaporasoI BorrecaA StancanelliF ManganelliL SantoroM Nolano

Published in: Neuropathology and applied neurobiology (2020)

Irregular spatial distribution is an SFN intrinsic feature preceding actual nerve loss. The presence of a stretch of denervated epidermis longer than 350 µm is a parameter able to increase the diagnostic efficiency of skin biopsy.

Keyphrases

wound healing
ultrasound guided
soft tissue
fine needle aspiration
peripheral nerve
machine learning