Asenapine modulates mood-related behaviors and 5-HT1A/7 receptors-mediated neurotransmission.
Sarah DelcourteErika AbrialAdeline EtiévantRenaud RoveraJørn ArntMichael DidriksenNasser HaddjeriPublished in: CNS neuroscience & therapeutics (2017)
These results confirm that Asenapine displays robust antimanic property and effective in vivo antagonistic activity at 5-HT1A/7 receptors.