The impact of obesity on severe disease and mortality in people with SARS-CoV-2: A systematic review and meta-analysis.
Samuel SeiduClare GilliesFrancesco ZaccardiSetor Kwadzo KunutsorJamie Hartmann-BoyceThomas YatesAwadhesh Kumar SinghMelanie J DaviesKamlesh KhuntiPublished in: Endocrinology, diabetes & metabolism (2020)
Excess adiposity is a risk factor for severe disease and mortality in people with SARS-CoV-2 infection. This was particularly pronounced in people 60 and older. The increased risk of worse outcomes from SARS-CoV-2 infection in people with excess adiposity should be taken into account when considering individual and population risks and when deciding on which groups to target for public health messaging on prevention and detection measures. Systematic review registration: PROSPERO 2020: CRD42020179783.
Keyphrases
- insulin resistance
- systematic review
- sars cov
- public health
- respiratory syndrome coronavirus
- weight gain
- cardiovascular events
- metabolic syndrome
- early onset
- meta analyses
- risk factors
- adipose tissue
- physical activity
- skeletal muscle
- high fat diet induced
- smoking cessation
- human health
- risk assessment
- coronary artery disease
- drug induced
- middle aged
- body mass index
- label free
- loop mediated isothermal amplification