Structural variant analysis of a cancer reference cell line sample using multiple sequencing technologies.

Keyur TalsaniaTsai-Wei ShenXiongfong ChenErich JaegerZhipan LiZhong ChenWanqiu ChenBao TranRebecca KuskoLimin WangAndy Wing Chun PangZhaowei YangSulbha ChoudhariMichael ColganLi Tai FangAndrew CarrollJyoti ShettyYuliya KrigaOksana GermanTatyana SmirnovaTiantain LiuJing LiBen KellmanKarl HongAlex R HastieAparna NatarajanAli MoshrefiAnastasiya GranatTiffany TruongRobin BombardiVeronnica MankinenDaoud MeerzamanChristopher E MasonJack CollinsEric StahlbergChunlin XiaoCharles WangWenming XiaoYongmei Zhao

Published in: Genome biology (2022)

A high-confidence consensus SV call set was established for the reference cancer cell line. A large subset of the variants identified was validated by multiple orthogonal methods.

Keyphrases

papillary thyroid
squamous cell
lymph node metastasis
gene expression
copy number
childhood cancer
young adults
genome wide