Lactobacillus acidophilus PIN7 paraprobiotic supplementation ameliorates DSS-induced colitis through anti-inflammatory and immune regulatory effects.

Yeon-Jin KyeSo-Young LeeHa-Ra KimByung-Hoo LeeJong-Hyun ParkMyeong-Soo ParkGeun-Eog JiMi-Kyung Sung

Published in: Journal of applied microbiology (2021)

Paraprobiotic L. acidophilus PIN7 ameliorated DSS-induced colitis by regulating immune-modulatory TLR6 signaling and gut microbiota composition SIGNIFICANCE AND IMPACT OF THE STUDY: This study suggests paraprobiotic L. acidophilus PIN7 are superior candidates to prevent intestinal inflammation associated with dysregulated immune responses.

Keyphrases

immune response
anti inflammatory
oxidative stress
toll like receptor
inflammatory response
transcription factor
mouse model
nuclear factor