Covert Brain Infarcts in Patients with Philadelphia Chromosome-Negative Myeloproliferative Disorders.
Polina I KuznetsovaAnton A RaskurazhevRodion N KonovalovMarina V KrotenkovaAndrey O ChechetkinOlga V LagodaAnait L MelikhyanMarine M TanashyanPublished in: Journal of clinical medicine (2021)
CBIs are common in patients with Ph-negative MPD. Arterial hypertension and carotid atherosclerosis were not associated with CBIs in this group of patients. The most significant factors in the development of CBIs were endothelial dysfunction (as measured by FMD) and high hemoglobin levels. Patients with Ph-negative MPD and CBIs were older and had more prevalent endothelial dysfunction.