Cognitive Reserve in Parkinson's Disease without Dementia: β-Amyloid and Metabolic Assessment.
Beatriz Fernández-RodríguezRafael Rodriguez-RojasPasqualina GuidaSantiago Angulo-Díaz-ParreñoClara TrompetaDavid Mata-MarínIgnacio ObesoLydia VelaIsabel Plaza de Las HerasJosé A ObesoCarmen Gasca-SalasPublished in: Movement disorders clinical practice (2024)
Higher CR in non-demented PD is associated with better cognitive performance, which might reduce vulnerability to the effect of β-amyloid. Whether superior CR leads to protection against metabolic deterioration, and predominantly right hemisphere involvement, deserves further exploration.