Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues.

Mariska A M SchröderFred C G J SweepAntonius E van HerwaardenRod T MitchellJitske EliveldAns M M van PeltAlan E RowanDarren KorbieNike M M L StikkelbroeckHedi L Claahsen-van der Grinten Paul N Span

Published in: European journal of endocrinology (2022)

Our data suggest that TART is induced - most likely via activation of a cAMP/protein kinase A-dependent receptor - from a progenitor cell into a unique mature adrenal-like cell type, sometimes exhibiting both adrenal and testicular features.

Keyphrases

protein kinase
gene expression
germ cell
high glucose
diabetic rats
electronic health record
binding protein
transcription factor
big data
oxidative stress
heat shock
artificial intelligence