Cerebrospinal fluid matrix metalloproteinase 9 levels, blood-brain barrier permeability, and treatment outcome in tuberculous meningitis.

Sharada MailankodyGurukiran V DangetiRajendiran SoundravallyNoyal M JosephJharna MandalTarun K DuttaTamilarasu Kadhiravan

Published in: PloS one (2017)

Our findings do not support the hypothesis that pretreatment levels of MMP9 would be higher in tuberculous meningitis patients experiencing a poor treatment outcome. Further, MMP9 levels in the CSF did not correlate with blood-brain barrier permeability in patients with tuberculous meningitis.

Keyphrases

blood brain barrier
cerebrospinal fluid
cerebral ischemia
end stage renal disease
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes