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Hydrogen-bonding-induced bathochromic effect of Si-coumarin and its use in monitoring adipogenic differentiation.

Chen LiTing WangNi LiMin LiYuntao LiYan SunYang TianJunru ZhuYiqian WuDazhi ZhangXiaoyan Cui
Published in: Chemical communications (Cambridge, England) (2019)
Introduction of a heteroatom into a fluorophore was carried out for coumarin through a replacement of its bridging oxygen atom with a silicon atom. The maximum-emission wavelength of Si-coumarin (SiC B) bathochromically shifted from 426 nm in cyclohexane to 626 nm in water. The adipogenic differentiation processes in mesenchymal stem cells were monitored using SiC B.
Keyphrases
  • fluorescent probe
  • mesenchymal stem cells
  • photodynamic therapy
  • molecular dynamics
  • room temperature
  • high glucose
  • umbilical cord
  • diabetic rats
  • bone marrow
  • electron transfer
  • stem cells
  • cell therapy
  • endothelial cells