Effects of CKMT1 on radiosensitivity of nasopharyngeal carcinoma cells.

Ruilong Lan Fei Huang Guangxian Zhong Ruiqing Chen Zeng Wang Junying Chen Lengxi Fu Jinsheng Hong Lurong Zhang

Published in: International journal of radiation biology (2019)

NPC cells with higher CKMT1 exhibited lower radiosensitivity through promoting phosphorylation of STAT3. Our findings suggest that CKMT1 may be an alternative radiotherapeutic target in NPC therapy.

Keyphrases

induced apoptosis
cell cycle arrest
cell proliferation
endoplasmic reticulum stress
signaling pathway
stem cells
oxidative stress
pi k akt