Adaptive Individualized high-dose preoperAtive (AIDA) chemoradiation in high-risk rectal cancer: a phase II trial.

Alessandra GuidoDajana CuicchiPaolo CastellucciFrancesco CelliniFrancesca Di FabioFabiola Lorena Rojas LlimpeLidia StrigariMilly BuwengeSavino CillaFrancesco DeodatoGabriella MacchiaErika GaliettaRita GolfieriAndrea ArdizzoniRocco Maurizio ZagariStefano FantiGilberto PoggioliLorenzo FuccioAlessio G Morganti

Published in: European journal of nuclear medicine and molecular imaging (2022)

Our results showed that a dose escalation on a reduced target in the final phase of CRT is well tolerated and able to provide a high pCR rate.

Keyphrases

rectal cancer
high dose
locally advanced
open label
low dose
stem cell transplantation
patients undergoing
cardiac resynchronization therapy
clinical trial
heart failure
real time pcr
squamous cell carcinoma
radiation therapy
study protocol