Steroids as rescue therapy for vitamin A-induced acute liver failure.
Anand V KulkarniPramod KumarRupjyoti TalukdarNagaraj P RaoPublished in: BMJ case reports (2020)
Antioxidant drugs form one of the mainstay therapies for pain management in chronic pancreatitis. Heightened oxidative stress and free radical activity is the target for the use of antioxidant therapy in chronic pancreatitis pain relief. One of the chief components of these drugs is beta-carotene, and vitamin A. Vitamin A is a proven hepatotoxic agent which can lead to liver injury ranging from acute hepatitis to cirrhosis. Here, we present a case of chronic pancreatitis who continued antioxidant therapy unsupervised for 7 years and developed vitamin A-induced acute liver failure, which was treated with prednisolone.
Keyphrases
- liver failure
- pain management
- oxidative stress
- liver injury
- drug induced
- hepatitis b virus
- chronic pain
- anti inflammatory
- machine learning
- ischemia reperfusion injury
- dna damage
- induced apoptosis
- diabetic rats
- stem cells
- neuropathic pain
- spinal cord injury
- cell therapy
- heat shock
- replacement therapy
- smoking cessation
- respiratory failure