Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease.

Veselin GrozdanovLuc BoussetMeike HoffmeisterCorinna BliederhaeuserChristoph MeierKarine MadionaLaura PieriMartin KiechlePamela J McLeanJan KassubekChristian BehrendsAlbert C LudolphJochen H WeishauptRonald MelkiKarin M Danzer

Published in: Annals of neurology (2019)

Taken together, our data suggest that α-synuclein pathology and dysregulation of monocytes in Parkinson disease can act together to induce excessive inflammatory responses to α-synuclein. ANN NEUROL 2019;86:593-606.

Keyphrases

parkinson disease
deep brain stimulation
neoadjuvant chemotherapy
electronic health record
squamous cell carcinoma
peripheral blood
locally advanced
radiation therapy
neural network
data analysis
weight loss
deep learning
rectal cancer