Comprehensive analysis of allergen-specific IgE in COPD: mite-specific IgE specifically related to the diagnosis of asthma-COPD overlap.

Hikaru ToyotaNaoya SugimotoKonomi KobayashiYuki SuzukiYuri TakeshitaAyaka ItoMariko UjinoFuminori TomyoHirokazu SakasegawaYuta KoizumiMichio KuramochiMasao YamaguchiHiroyuki Nagase

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2021)

The prominent role of mite-specific IgE in the diagnosis and pathology of ACO and the potentially detrimental effect of cockroach sensitization on air trapping in COPD were suggested. The finding highlights the future development of a treatment targeting IgE as a treatable trait in COPD.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
cystic fibrosis
air pollution
genome wide
current status
drug induced
drug delivery
replacement therapy