Consensus: guidelines: best practices for detection, assessment and management of suspected acute drug-induced liver injury during clinical trials in patients with nonalcoholic steatohepatitis.
Arie RegevMelissa PalmerMark I AviganLara Dimick-SantosWilliam R TreemJohn F MarcinakDaniel SeekinsGopal KrishnaFrank A AnaniaJames W FrestonJames H LewisArun J SanyalNaga ChalasaniPublished in: Alimentary pharmacology & therapeutics (2019)
This paper provides a framework for the approach to assessment and management of suspected acute DILI during clinical trials in patients with NASH.
Keyphrases
- clinical trial
- drug induced
- liver failure
- respiratory failure
- pulmonary embolism
- aortic dissection
- healthcare
- clinical practice
- primary care
- phase ii
- study protocol
- adverse drug
- extracorporeal membrane oxygenation
- open label
- acute respiratory distress syndrome
- loop mediated isothermal amplification
- quantum dots
- phase iii
- real time pcr
- electronic health record