δ-Tocotrienol induces apoptosis, involving endoplasmic reticulum stress and autophagy, and paraptosis in prostate cancer cells.

Fabrizio FontanaRoberta Manuela MorettiMichela RaimondiMonica MarzagalliGiangiacomo BerettaPatrizia ProcacciPatrizia SartoriMarina Montagnani MarelliPatrizia Limonta

Published in: Cell proliferation (2019)

These data demonstrate that apoptosis, involving ER stress and autophagy (in autophagy positive PC3 cells), and paraptosis are involved in the anti-cancer activity of δ-TT in CRPC cells.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
oxidative stress
cell cycle arrest
cell death
machine learning