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Low-Dose CT Image Denoising with Improving WGAN and Hybrid Loss Function.

Zhihua LiWeili ShiQiwei XingMiao YuWei HeHuamin YangZhengang Jiang
Published in: Computational and mathematical methods in medicine (2021)
The X-ray radiation from computed tomography (CT) brought us the potential risk. Simply decreasing the dose makes the CT images noisy and diagnostic performance compromised. Here, we develop a novel denoising low-dose CT image method. Our framework is based on an improved generative adversarial network coupling with the hybrid loss function, including the adversarial loss, perceptual loss, sharpness loss, and structural similarity loss. Among the loss function terms, perceptual loss and structural similarity loss are made use of to preserve textural details, and sharpness loss can make reconstruction images clear. The adversarial loss can sharp the boundary regions. The results of experiments show the proposed method can effectively remove noise and artifacts better than the state-of-the-art methods in the aspects of the visual effect, the quantitative measurements, and the texture details.
Keyphrases
  • computed tomography
  • low dose
  • image quality
  • deep learning
  • positron emission tomography
  • magnetic resonance imaging
  • high dose
  • optical coherence tomography
  • mass spectrometry
  • ionic liquid
  • radiation induced