Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis.

Hewei XiongSen RenJing ChenXiaofan YangYutian LiuZhao XuJiahe GuoTao JiangMeng YuanYang LiuGuolei ZhangWenqing LiHans-Günther MachensZhenbing Chen

Published in: Stem cell research & therapy (2023)

The lncRNA SAN mediates ASC senescence by regulating the miR-143-3p/ADD3 pathway, providing a potential target for rejuvenation of senescent ASCs and enhancement of wound repair.

Keyphrases

long noncoding rna
wound healing
dna damage
endothelial cells
human health
surgical site infection
oxidative stress
risk assessment