Considerations for observational study design: Comparing the evidence of opioid use between electronic health records and insurance claims.
Jessica C YoungNabarun DasguptaTil StürmerVirginia PateMichele Jonsson FunkPublished in: Pharmacoepidemiology and drug safety (2022)
When characterizing opioid exposure, we found substantial discrepancies between EHR medication orders and prescription claims data. In all time periods assessed, most patients' use was reflected only in the EHR, or only in the claims, not both. The potential for misclassification of drug utilization must be evaluated carefully, and choice of data source may have large impacts on key study design elements.
Keyphrases
- electronic health record
- health insurance
- adverse drug
- clinical decision support
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- chronic pain
- peritoneal dialysis
- healthcare
- prognostic factors
- affordable care act
- pain management
- emergency department
- patient reported outcomes
- risk assessment
- deep learning
- drug induced
- patient reported