Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study.
Sophie PapaAntonella AdamiMichael MetoudiRichard BeatsonMolly Sarah GeorgeDaniela AchkovaEvangelia WilliamsSefina ArifFiona ReidMaria ElstadNicholas Beckley-HoelscherAbdel DouriMarc DelordMike LyneDharshene ShivapathamChristopher FisherAndrew HopeSakina GooljarArindam MitraLinda GommCienne MortonRhonda Henley-SmithSelvam ThavarajAlice SantambrogioCynthia Lilian AndoniadouSarah AllenVictoria GibsonGary J R CookAna C Parente-PereiraDavid M DaviesFarzin FarzanehAnna SchurichTeresa Guerrero-UrbanoJean-Pierre JeannonJames SpicerJohn MaherPublished in: Journal for immunotherapy of cancer (2023)
These data demonstrate the safe intratumoral administration of T4 immunotherapy in advanced HNSCC.