Mortality after radical prostatectomy in a matched contemporary cohort in Sweden compared to the Scandinavian Prostate Cancer Group 4 (SPCG-4) study.

Walter CazzanigaHans GarmoDavid L RobinsonLars HolmbergAnna Bill-AxelsonPär Stattin

Published in: BJU international (2018)

Outcomes after RP for men in the SPCG-4 cannot be directly applied to men in the current era, mainly due to grade inflation and grade migration. However, by compensating for changes in grading, similar outcomes after RP were seen in the SPCG-4 and NPCR. In order to compare historical trials with current treatments, data on temporal changes in detection, diagnostics, and treatment have to be accounted for.

Keyphrases

radical prostatectomy
prostate cancer
middle aged
electronic health record
big data
machine learning
loop mediated isothermal amplification
label free
replacement therapy