Novel mutations in NSP-1 and PLPro of SARS-CoV-2 NIB-1 genome mount for effective therapeutics.

Mohammad Uzzal HossainArittra BhattacharjeeMd Tabassum Hossain EmonZeshan Mahmud ChowdhuryIshtiaque AhammadMd Golam MosaibMd MoniruzzamanMd Hadisur RahmanMd Nazrul IslamIrfan AhmedMd Ruhul AminAsif RashedKeshob Chandra DasChaman Ara KeyaArittra Bhattacharjee

Published in: Journal, genetic engineering & biotechnology (2021)

Mutants of NSP-1 could provide attenuated vaccines against coronavirus. Also, these mutations of PLPro might be targeted to develop better anti-SARS therapeutics. We hope our study will help to get better insides during the development of attenuated vaccine and PLPro inhibitors.

Keyphrases

sars cov
small molecule
respiratory syndrome coronavirus
cancer therapy
gene expression