Relapse of a group 4 medulloblastoma after 18 years as proven by histology and DNA methylation profiling.

Franz L RicklefsFriederike FritzscheBeate WinklerBarbara MeissnerLasse DührsenManfred WestphalStefan RutkowskiTobias MartensFranz L Ricklefs

Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2019)

Our case not only illustrates the potential of very late recurrences after seemingly cured group 4 MB, but also illustrates that detailed molecular analyses are indispensable in patients with a history of a previous malignancy.

Keyphrases

dna methylation
gene expression
genome wide
single cell
free survival
human health
climate change
copy number