Association of serum Spp1 levels with disease progression in ALS and SBMA.
Woohee JuJae-Jun BanHye-Ryeong ImSun Hi KoJaewoo SeoYoung-Gi MinYoon Ho HongSeok-Jin ChoiJung Joon SungPublished in: Annals of clinical and translational neurology (2024)
Neuroinflammation does not appear to be a primary contributor to the pathogenesis of SBMA. Serum Spp1 levels may serve as a reliable biomarker for disease progression and prognosis in ALS. These findings expand our understanding of these two distinct motor neuron disorders and offer a potential biomarker for future studies.