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Myocardial perfusion cardiovascular magnetic resonance: optimized dual sequence and reconstruction for quantification.

Peter KellmanMichael S HansenSonia Nielles-VallespinJannike NickanderRaquel ThemudoMartin UganderHui Xue
Published in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2017)
A dual sequence for myocardial perfusion cardiovascular magnetic resonance and AIF measurement has been optimized for quantification of myocardial blood flow. A validation in phantoms was performed to confirm that the signal conversion to gadolinium concentration was linear. The proposed sequence was integrated with a fully automatic in-line solution for pixel-wise mapping of myocardial blood flow and evaluated in adenosine stress and rest studies on N = 29 normal healthy subjects. Reliable perfusion mapping was demonstrated and produced estimates with low variability.
Keyphrases
  • blood flow
  • magnetic resonance
  • contrast enhanced
  • high resolution
  • left ventricular
  • amino acid
  • high density
  • magnetic resonance imaging
  • machine learning
  • computed tomography
  • heart failure