Myocardial perfusion cardiovascular magnetic resonance: optimized dual sequence and reconstruction for quantification.
Peter KellmanMichael S HansenSonia Nielles-VallespinJannike NickanderRaquel ThemudoMartin UganderHui XuePublished in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2017)
A dual sequence for myocardial perfusion cardiovascular magnetic resonance and AIF measurement has been optimized for quantification of myocardial blood flow. A validation in phantoms was performed to confirm that the signal conversion to gadolinium concentration was linear. The proposed sequence was integrated with a fully automatic in-line solution for pixel-wise mapping of myocardial blood flow and evaluated in adenosine stress and rest studies on N = 29 normal healthy subjects. Reliable perfusion mapping was demonstrated and produced estimates with low variability.