Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus.
Fatemeh Hassani NiaDaniel WoikeVictoria MartensMalte KlüssendorfHans-Hinrich HönckSönke HarderHans-Jürgen KreienkampPublished in: Molecular autism (2020)
Our data show that the interaction between Shank3 N-terminus and δ-catenin is required for the postsynaptic targeting of δ-catenin. Failure of proper targeting of δ-catenin to postsynaptic sites may contribute to the pathogenesis of autism spectrum disorder.