Cryoablation does not significantly contribute to systemic effector immune responses in poorly immunogenic B16F10 melanoma model.

Cryoablation does not significantly contribute to systemic, anti-tumor, effector immune responses in a B16F10 melanoma model. Cryoablation primarily performs tumor debulking, and immunotherapy functions independently of cryoablation in eliciting anti-tumor effector immune responses.