Clinical impact of CA-125 ELIMination rate constant K (KELIM) on surgical strategy in advanced serous ovarian cancer patients.
Barnabe BouvarelOliver ColombanJean-Sebastien FrenelCécile LoaecCharlotte BourginDominique BertonGilles FreyerBenoit YouJean-Marc ClassePublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2024)
Primary tumor chemosensitivity, assessed by the modeled CA-125 KELIM, calculated during neoadjuvant chemotherapy, is a major parameter to consider for decision making regarding interval surgery. Complementary to the RECIST score and laparoscopy, this non-invasive tool, available online, helps tailor the interval surgery strategy according to patient tumor chemosensitivity.