PARP Inhibitors in Combination with Radiotherapy: To Do or Not to Do?

Amelia BarcelliniPierre LoapKazutoshi MurataRiccardo VillaYoulia M Kirova Noriyuki OkonogiEster Orlandi

Published in: Cancers (2021)

despite the heterogeneity of the evaluated patient populations and tumor types, and the limited number of the studies, this review suggests that a combination approach is feasible even though the efficacy profile remains unclear.

Keyphrases

early stage
dna damage
case report
radiation therapy
locally advanced
radiation induced
case control
squamous cell carcinoma
oxidative stress
rectal cancer