Re-evaluating the mythical divide between traditional and novel cardiovascular risk factors in rheumatoid arthritis.
Eirik IkdahlMats Julius StensrudPublished in: RMD open (2024)
Cardiovascular (CV) risk factors for rheumatoid arthritis (RA) are conventionally classified as 'traditional' and 'novel'. We argue that this classification is obsolete and potentially counterproductive. Further, we discuss problems with the common practice of adjusting for traditional CV risk factors in statistical analyses. These analyses do not target well-defined effects of RA on CV risk. Ultimately, we propose a future direction for cardiorheumatology research that prioritises optimising current treatments and identifying novel therapeutic targets over further categorisation of well-known risk factors.
Keyphrases
- rheumatoid arthritis
- risk factors
- cardiovascular risk factors
- disease activity
- ankylosing spondylitis
- interstitial lung disease
- cardiovascular disease
- metabolic syndrome
- mental health
- primary care
- machine learning
- healthcare
- systemic lupus erythematosus
- current status
- quality improvement
- systemic sclerosis
- breast cancer risk